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FSHW: 乌龙茶提取物及其代谢产物对高脂饮食诱导的肥胖Wistar大鼠的影响

放大字体  缩小字体 发布日期:2018-08-17
核心提示:肥胖在全世界是一个重要的健康问题。长期以来,为健康和快乐而喝茶的概念被人们广泛接受。
   肥胖在全世界是一个重要的健康问题。长期以来,为健康和快乐而喝茶的概念被人们广泛接受。
 
  Andraca theae菌株在茶叶上生长,但是其排泄物中代谢产物的生物活性尚不清楚。
 
  因此,在最新一期的《Food Science and Human Wellness》中,来自台湾大学食品科学与技术学院的Yen-Chen Tung、Tsung-Hai Hsieh和茶园研究与推广站的Meei-Ju Yang等人刊登了他们对于茶叶提取物(台湾茶实验站12号(TE))及其来自Andraca theae(TME)的代谢物是否可以预防高脂饮食诱导的肥胖大鼠肥胖的研究成果。
 
  研究结果表明,TE的儿茶素没食子酸盐(EGCG)和咖啡因浓度高于TME。TE通过增加前脂肪细胞因子1(Pref-1)、SRY(性别决定区Y)-box 9(SOX-9)减少过氧化物酶体增殖物激活受体γ(PPARγ)、CCAAT /增强子结合蛋白(C / EBP)β、C /EBPα和C /EBPγ蛋白的表达显着降低了腹部脂肪组织,尤其是附睾脂肪。
 
  结论
 
  综上所述,这些结果表明,TE茶中茶多酚的含量对减轻腹部脂肪起着重要作用。
 
  文章摘要
 
  ABSTRACT
 
  The effects ofthe extract of oolong tea and its metabolites from
 
  Andraca theae in high fat diet induced obese Wistar rat
 
  Yen-ChenTunga,1, Tsung-Hai Hsieha,1, Meei-Ju Yangb,Wei-Lun Hungc, Chi-Tang Hod,
 
  Min-HsiungPana,*
 
  a Institute of Food Science and Technology,National Taiwan University, Taipei 106, Taiwan, China
 
  b Tea Research and Extension Station, Taoyuan326, Taiwan, China
 
  c Citrus Research and Education Center,Department of Food Science and Human Nutrition, University of Florida, LakeAlfred, FL, 33850, USA
 
  d Department of Food Science, Rutgers University, New Brunswick, NJ 08901, USA
 
  Abstract
 
  Obesity is a criticalhealth issue worldwide. For a long time, the concept of drinking tea for healthand pleasure is widely accepted. The strain of Andraca theae lives on the tea leafand the bioactivity of its metabolites in the feces is unknown yet. Thus, theobjective of this study was to investigate whether the extract of tea (TaiwanTea Experiment Station No.12 (TE)) and its metabolites from Andraca theae (TME) could preventobesity in the high fat diet-induced obese rats. Our results showed that TE hadhigher concentrations of epigallocatechin gallate (EGCG) and caffeine than thatfrom TME. TE significantly decreased abdominal adipose tissue, especiallyepididymal fat via increasing preadipocyte factor 1 (Pref-1), SRY (sexdetermining region Y)-box 9 (SOX-9) and decreasing peroxisomeproliferator-activated receptor γ (PPARγ), CCAAT/enhancer binding protein(C/EBP)β, C/EBPα and C/EBPγ protein expression.Taken together, these results suggest that the content of tea polyphenols in TEplay an important role for alleviating abdominal fat.
 
 
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